Dr. rer. Nat. Hansjörg Baurecht
Aktuelle Publikationen
2017
2016Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YA, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WH, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Weidinger S
Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
J Allergy Clin Immunol 2016;137(1):130-6 | Manz J, Rodríguez E, ElSharawy A, Oesau EM, Petersen BS, Baurecht H, Mayr G, Weber S, Harder J, Reischl E, Schwarz A, Novak N, Franke A, Weidinger S
Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk
J Invest Dermatol 2016;[Epub ahead of print] |
2015Koch M, Baurecht H, Ried JS, Rodriguez E, Schlesinger S, Volks N, Gieger C, Rückert IM, Heinrich L, Willenborg C, Smith C, Peters A, Thorand B, Koenig W, Lamina C, Jansen H, Kronenberg F, Seissler J, Thiery J, Rathmann W, Schunkert H, Erdmann J, Barker J, Nair RP, Tsoi LC, Elder JT, Mrowietz U, Weichenthal M, Mucha S, Schreiber S, Franke A, Schmitt J, Lieb W, Weidinger S.
Psoriasis and Cardiometabolic Traits: Modest Association but Distinct Genetic Architectures.
J Invest Dermatol. 2015;135(5):1283-93 | Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus
D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger
C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I,
McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan
GM; PAGE Consortium, Schreiber S, Smith C, Strauch K, Stuart PE,
Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S,
Cordell HJ, Brown SJ
Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis
Gives Insight into Opposing Genetic Mechanisms.
Am J Hum Genet. 2015;96(1):104-20 | Schaarschmidt H, Ellinghaus D, Rodríguez E, Kretschmer A, Baurecht H, Lipinski S, Meyer-Hoffert U, Harder J, Lieb W, Novak N, Fölster-Holst R, Esparza-Gordillo J, Marenholz I, Ruschendorf F, Hubner N, Reischl E, Waldenberger M, Gieger C, Illig T, Kabesch M, Zhang XJ, Xiao FL, Lee YA, Franke A, Weidinger S
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis
J Allergy Clin Immunol. 2015;136(3):802-6 | Weidinger S, Baurecht H, Schmitt J
A critical appraisal of the petite study report: Topical corticosteroids are safe and effective in the long-term treatment of infantile atopic dermatitis.
Pediatrics 2015;136:e1485 | Fischer A, Ellinghaus D, Nutsua M, Hofmann S, Montgomery CG, Iannuzzi MC, Rybicki BA, Petrek M, Mrazek F, Pabst S, Grohe C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Mihailovic-Vucinic V, Jovanovic D, Sterclova M, Homolka J, Nothen MM, Herms S, Gieger C, Strauch K, Winkelmann J, Boehm BO, Brand S, Buning C, Schurmann M, Ellinghaus E, Baurecht H, Lieb W, Nebel A, Muller-Quernheim J, Franke A, Schreiber S
Identification of immune-relevant factors conferring sarcoidosis genetic risk.
Am. J. Respir. Crit. Care Med. 2015;192:727-736 | Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF; Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM,
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Nature Genetics 2015;47(12):1449-56 | Interleukin 1 Genetics Consortium.
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.
Lancet Diabetes Endocrinol 2015;Jun;3(6):e4. | Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MA, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA.
Meta-analysis identifies seven susceptibility loci involved in the atopic march
Nat Commun 2015;Nov 6;6:e8804 |
2014Fischer J, Wu Z, Kantyka T, Sperrhacke M, Dimitrieva O, Koblyakova Y, Ahrens K, Graumann N, Baurecht H, Reiss K, Schröder JM, Proksch E, Meyer-Hoffert U
Characterization of Spink6 in Mouse Skin: The Conserved Inhibitor of Kallikrein-Related Peptidases Is Reduced by Barrier Injury.
J Invest Dermatol. 2014;134(5):1305-12 | Hotze M, Baurecht H, Rodríguez E, Chapman-Rothe N, Ollert M, Fölster-Holst R, Adamski J, Illig T, Ring J, Weidinger S
Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum levels of phosphatidylcholines.
Allergy 2014;69(1):132-5 | Gerdes S, Laudes M, Neumann K, Baurecht H, Mrowietz U.
Wnt5a - a potential factor linking psoriasis to metabolic complications.
Exp Dermatol. 2014;23(6):438-40 | Gerdes S, Osadtschy S, Buhles N, Baurecht H, Mrowietz U.
Cardiovascular biomarkers in patients with psoriasis.
Exp Dermatol. 2014;23(5):322-5 | Rodríguez E, Baurecht H, Wahn AF, Kretschmer A, Hotze M, Zeilinger S, Klopp N, Illig T, Schramm K, Prokisch H, Gieger C, Harder J, Cifuentes L, Novak N, Weidinger S
An integrated epigenetic and transcriptomic analysis reveals distinct patterns of DNA methylation associated with atopic dermatitis.
Journal of Investigative Dermatology 2014;134(7):1873-83 |
2013Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodriguez E, Matanovic A, Marenholz I, Hubner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nothen MM, Folster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Buning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis
Nat Genet 2013;45: 808-812 | Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Hum Mol Genet. 2013;22(23):4841-56 | Ried JS, Baurecht H, Stückler F, Krumsiek J, Gieger C, Heinrich J, Kabesch M, Prehn C, Peters A, Rodriguez E, Schulz H, Strauch K, Suhre K, Wang-Sattler R, Wichmann HE, Theis FJ, Illig T, Adamski J, Weidinger S.
Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma
Allergy 2013;68(5):629-36 | Zeilinger S, Kühnel B, Klopp N, Baurecht H, Kleinschmidt A, Gieger C, Weidinger S, Lattka E, Adamski J, Peters A, Strauch K, Waldenberger M, Illig T
Tobacco smoking leads to extensive genome-wide changes in DNA methylation.
PLoS One 2013;8(5):e63812 | Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
J Allergy Clin Immunol. 2013;132(5):1121-9 |
2012Rebane A, Zimmermann M, Aab A, Baurecht H, Koreck A, Karelson M, Abram K, Metsalu T, Pihlap M, Meyer N, Fölster-Holst R, Nagy N, Kemeny L, Kingo K, Vilo J, Illig T, Akdis M, Franke A, Novak N, Weidinger S, Akdis CA.
Mechanisms of IFN-?-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis
J Allergy Clin Immunol. 2012;129(5):1297-306 | Liedén A, Winge MC, Sääf A, Kockum I, Ekelund E, Rodriguez E, Fölster-Holst R, Franke A, Illig T, Tengvall-Linder M, Baurecht H, Weidinger S, Wahlgren CF, Nordenskjöld M, Bradley M
Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.
PLoS One 2012;7(11):e49694 | Arnold M, Hartsperger ML, Baurecht H, Rodríguez E, Wachinger B, Franke A, Kabesch M, Winkelmann J, Pfeufer A, Romanos M, Illig T, Mewes HW, Stümpflen V, Weidinger S.
Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.
BMC Genomics. 2012;2(9):1067-75 |
2011Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken
A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C,
von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S,
Wichmann HE, Heinrich J, Weidinger S; GINIplus and LISAplus study groups
Predictive value of food sensitization and filaggrin mutations in
children with eczema
J Allergy Clin Immunol 2011;Dec;128(6):1235-1241 | Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P; Australian Asthma Genetics Consortium (AAGC), Pourcain BS, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C; The Genetics of Overweight Young Adults (GOYA) Consortium, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM; the Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Weidinger S.
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Nat. Genet. 2011;44(2):187-192 | Naumann A, Söderhäll C, Fölster-Holst R, Baurecht H, Harde V, Müller-Wehling K, Rodríguez E, Ruether A, Franke A, Wagenpfeil S, Novak N, Mempel M, Kalali BN, Allgaeuer M, Koch J, Gerhard M, Melén E, Wahlgren CF, Kull I, Stahl C, Pershagen G, Lauener R, Riedler J, Doekes G, Scheynius A, Illig T, von Mutius E, Schreiber S, Kere J, Kabesch M, Weidinger S.
A comprehensive analysis of the COL29A1 gene does not support a role in eczema.
J Allergy Clin Immunol 2011;127(5):1187-94 | Maintz L, Yu CF, Rodríguez E, Baurecht H, Bieber T, Illig T, Weidinger S, Novak N.
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities.
Allergy 2011;66(7):893-902 |
2010Jungersted JM, Scheer H, Mempel M, Cifuentes L, Baurecht H, Høgh JK, Hellgren LI, Jemec GBE, Agne T, Weidinger S
Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
Allergy 2010;65:911-8 |
2009Esparza-Gordillo J*, Weidinger S*, Fölster-Holst R, Bauerfeind A, Ruschendorf F, Patone G, Rhode K, Marenholz I, Schulz1 F, Hübner N, Wahn U, Schreiber S, Franke A, Vogler R, Baurecht H, Novak N, Rodriguez E, Illig T, Lee YA, Rüther A
A common variant on chromosome 11q13 is associated with atopic dermatitis
Nat Genet 2009;41:596-601 | Rodriguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S
Meta analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease
J Allergy Clin Immunol 2009;123:1361-70 |
2008Weidinger S, Baurecht H, Wagenpfeil S,, Henderson J, Novak N, Sandilands A, Chen H, Rodriguez E, O’Regan GM, Watson R, Liao H, Zhao Y, Barker JNWN, Allen M, Reynolds N, Meggitt S, Northstone K, Smith GD, Strobl C, Stahl C, Kneib T, Klopp N, Bieber T, Behrendt H, Palmer CNA, Wichmann HE, Ring J, Illig T, McLean WHI, Irvine AD
Analysis of the individual and aggregate genetic contributions of previously identified SPINK5, KLK7 and FLG polymorphisms to eczema risk
J Allergy Clin Immunol 2008;122:560-8 | Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, Gohlke H, Wagenpfeil S,, Ollert M, Ring J, Behrendt H, Heinrich J, Novak N, Bieber T, Kramer U, Berdel D, von Berg A, Bauer CP, Herbarth O, Koletzko S, Prokisch H, Mehta , Meitinger T, Depner M, von Mutius E, Liang L, Moffatt M, Cookson WO, Kabesch M, Wichmann HE, Illig T
Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus
PLoS Genet 2008;4(8):e1000166 | Weidinger S, O’Sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland S, McLean WHI, von Mutius E, Irvine AD, Kabesch M.
Filaggrin mutations, atopic eczema, hay fever and asthma in children
J Allergy Clin Immunol 2008;121:1203-1209 | Novak N, Baurecht H, Schäfer T, Rodriguez E, Wagenpfeil S, Klopp N, Heinrich J, Behrendt H, Ring J, Wichmann E, Illig T, Weidinger S
Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel
J Invest Dermatol 2008;128:1430-5 |
2007
2006Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CN, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WH, Novak N
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
J Allergy Clin Immunol 2006;118:214-9 |
2005
2004
2003
2002
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