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Prof. Dr. med. Stephan Weidinger
Aktuelle Publikationen


2017

Keine Einträge

2016

Zink A, Gensbaur A, Zirbs M, Seifert F, Suarez IL, Mourantchanian V, Weidinger S, Mempel M, Ring J, Ollert M
Targeting IgE in Severe Atopic Dermatitis with a Combination of Immunoadsorption and Omalizumab
Acta Derm Venereol. 2016;96(1):72-6
Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YA, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WH, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Weidinger S
Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
J Allergy Clin Immunol 2016;137(1):130-6
Saulite I, Hoetzenecker W, Weidinger S, Cozzio A, Guenova E, Wehkamp U
Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets.
Biomed Res Int 2016;[Epub ahead of print]
Manz J, Rodríguez E, ElSharawy A, Oesau EM, Petersen BS, Baurecht H, Mayr G, Weber S, Harder J, Reischl E, Schwarz A, Novak N, Franke A, Weidinger S
Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk
J Invest Dermatol 2016;[Epub ahead of print]

2015

Koch M, Baurecht H, Ried JS, Rodriguez E, Schlesinger S, Volks N, Gieger C, Rückert IM, Heinrich L, Willenborg C, Smith C, Peters A, Thorand B, Koenig W, Lamina C, Jansen H, Kronenberg F, Seissler J, Thiery J, Rathmann W, Schunkert H, Erdmann J, Barker J, Nair RP, Tsoi LC, Elder JT, Mrowietz U, Weichenthal M, Mucha S, Schreiber S, Franke A, Schmitt J, Lieb W, Weidinger S.
Psoriasis and Cardiometabolic Traits: Modest Association but Distinct Genetic Architectures.
J Invest Dermatol. 2015;135(5):1283-93
Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM; PAGE Consortium, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ
Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms.
Am J Hum Genet. 2015;96(1):104-20
Rodríguez E, Weidinger S
Genetics of atopic eczema. An update
Hautarzt 2015;66(2):84-9
Schaarschmidt H, Ellinghaus D, Rodríguez E, Kretschmer A, Baurecht H, Lipinski S, Meyer-Hoffert U, Harder J, Lieb W, Novak N, Fölster-Holst R, Esparza-Gordillo J, Marenholz I, Ruschendorf F, Hubner N, Reischl E, Waldenberger M, Gieger C, Illig T, Kabesch M, Zhang XJ, Xiao FL, Lee YA, Franke A, Weidinger S
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis
J Allergy Clin Immunol. 2015;136(3):802-6
Yin X, Low HQ, Wang L, Li Y, Ellinghaus E, Han J, Estivill X, Sun L, Zuo X, Shen C, Zhu C, Zhang A, Sanchez F, Padyukov L, Catanese JJ, Krueger GG, Duffin KC, Mucha S, Weichenthal M, Weidinger S, Lieb W, Foo JN, Li Y, Sim K, Liany H, Irwan I, Teo Y, Theng CT, Gupta R, Bowcock A, De Jager PL, Qureshi AA, de Bakker PI, Seielstad M, Liao W, Ståhle M, Franke A, Zhang X, Liu J
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
Nat Commun 2015;23;6:e6916
Tsoi LC, Spain SL, Ellinghaus E, Stuart PE, Capon F, Knight J, Tejasvi T, Kang HM, Allen MH, Lambert S, Stoll SW, Weidinger S, Gudjonsson JE, Koks S, Kingo K, Esko T, Das S, Metspalu A, Weichenthal M, Enerback C, Krueger GG, Voorhees JJ, Chandran V, Rosen CF, Rahman P, Gladman DD, Reis A, Nair RP, Franke A, Barker JN, Abecasis GR, Trembath RC, Elder JT.
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
Nat Commun 2015;5;6:e7001
Thijs J, Krastev T, Weidinger S, Buckens CF, de Bruin-Weller M, Bruijnzeel-Koomen C, Flohr C, Hijnen D
Biomarkers for atopic dermatitis: a systematic review and meta-analysis
Curr Opin Allergy Clin Immunol 2015;15(5):453-460
Weidinger S, Baurecht H, Schmitt J
A critical appraisal of the petite study report: Topical corticosteroids are safe and effective in the long-term treatment of infantile atopic dermatitis.
Pediatrics 2015;136:e1485
Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MA, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA.
Meta-analysis identifies seven susceptibility loci involved in the atopic march
Nat Commun 2015;Nov 6;6:e8804
Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF; Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell L, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM,
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Nature Genetics 2015;47(12):1449-56
Interleukin 1 Genetics Consortium.
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.
Lancet Diabetes Endocrinol 2015;Jun;3(6):e4.
Stuart PE, Nair RP, Tsoi LC, Tejasvi T, Das S, Kang HM, Ellinghaus E, Chandran V, Callis-Duffin K, Ike R, Li Y, Wen X, Enerbäck C, Gudjonsson JE, Kõks S, Kingo K, Esko T, Mrowietz U, Reis A, Wichmann HE, Gieger C, Hoffmann P, Nöthen MM, Winkelmann J, Kunz M, Moreta EG, Mease PJ, Ritchlin CT, Bowcock AM, Krueger GG, Lim HW, Weidinger S, Weichenthal M, Voorhees JJ, Rahman P, Gregersen PK, Franke A, Gladman DD, Abecasis GR, Elder JT.
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
Am J Hum Genet. 2015;97(6):816-36

2014

Hotze M, Baurecht H, Rodríguez E, Chapman-Rothe N, Ollert M, Fölster-Holst R, Adamski J, Illig T, Ring J, Weidinger S
Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum levels of phosphatidylcholines.
Allergy 2014;69(1):132-5
Brüske I, Standl M, Weidinger S, Klümper C, Hoffmann B, Schaaf B, Herbarth O, Lehmann I, von Berg A, Berdel D, Bauer CP, Koletzko S, Heinrich J, Lisaplus Study Groups FT
Epidemiology of urticaria in infants and young children in Germany - Results from the German LISAplus and GINIplus Birth Cohort Studies
Pediatr Allergy Immunol. 2014;25(1):36-42
Lapp T, Auw-Haedrich C, Reinhard T, Evans R, Rodríguez E, Weidinger S, Jakob T
Analysis of filaggrin mutations and expression in corneal specimens from patients with or without atopic dermatitis.
Int Arch Allergy Immunol. 2014;163(1):20-4
Kezic S, Novak N, Jakasa I, Jungersted JM, Simon M, Brandner JM, Middelkamp-Hup MA, Weidinger S
Skin barrier in atopic dermatitis.
Front Biosci (Landmark Ed) 2014;19:542-56
Schmitt J, Weidinger S
Alternative models of comorbidity: a framework for the interpretation of epidemiological association studies.
J Invest Dermatol. 2014;134(2):303-7
Rodríguez E, Weidinger S
Genome-associated studies in chronic inflammatory dermatoses
Internist (Berl). 2014;55(2):148-55
Weidinger S, Novak N
Atopic dermatitis revisited
Allergy 2014;69(1):1-2
Rodríguez E, Baurecht H, Wahn AF, Kretschmer A, Hotze M, Zeilinger S, Klopp N, Illig T, Schramm K, Prokisch H, Gieger C, Harder J, Cifuentes L, Novak N, Weidinger S
An integrated epigenetic and transcriptomic analysis reveals distinct patterns of DNA methylation associated with atopic dermatitis.
Journal of Investigative Dermatology 2014;134(7):1873-83

2013

Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodriguez E, Matanovic A, Marenholz I, Hubner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nothen MM, Folster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Buning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis
Nat Genet 2013;45: 808-812
Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Hum Mol Genet. 2013;22(23):4841-56
Ried JS, Baurecht H, Stückler F, Krumsiek J, Gieger C, Heinrich J, Kabesch M, Prehn C, Peters A, Rodriguez E, Schulz H, Strauch K, Suhre K, Wang-Sattler R, Wichmann HE, Theis FJ, Illig T, Adamski J, Weidinger S.
Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma
Allergy 2013;68(5):629-36
Esparza-Gordillo J, Schaarschmidt H, Liang L, Cookson W, Bauerfeind A, Lee-Kirsch MA, Nemat K, Henderson J, Paternoster L, Harper JI, Mangold E, Nothen MM, Rüschendorf F, Kerscher T, Marenholz I, Matanovic A, Lau S, Keil T, Bauer CP, Kurek M, Ciechanowicz A, Macek M, Franke A, Kabesch M, Hubner N, Abecasis G, Weidinger S, Moffatt M, Lee YA.
A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
J Allergy Clin Immunol. 2013;132(2):371-7
Zeilinger S, Kühnel B, Klopp N, Baurecht H, Kleinschmidt A, Gieger C, Weidinger S, Lattka E, Adamski J, Peters A, Strauch K, Waldenberger M, Illig T
Tobacco smoking leads to extensive genome-wide changes in DNA methylation.
PLoS One 2013;8(5):e63812
Schmitt J, Apfelbacher C, Heinrich J, Weidinger S, Romanos M
Association of atopic eczema and attention-deficit/hyperactivity disorder - meta-analysis of epidemiologic studies
Z Kinder Jugendpsychiatr Psychother. 2013;41(1):35-42
Bønnelykke K, Matheson MC, Pers TH, Granell R, Strachan DP, Alves AC, Linneberg A, Curtin JA, Warrington NM, Standl M, Kerkhof M, Jonsdottir I, Bukvic BK, Kaakinen M, Sleimann P, Thorleifsson G, Thorsteinsdottir U, Schramm K, Baltic S, Kreiner-Møller E, Simpson A, St Pourcain B, Coin L, Hui J, Walters EH, Tiesler CM, Duffy DL, Jones G, Ring SM, McArdle WL, Price L, Robertson CF, Pekkanen J, Tang CS, Thiering E, Montgomery GW, Hartikainen AL, Dharmage SC, Husemoen LL, Herder C, Kemp JP, Elliot P, James A, Waldenberger M, Abramson MJ, Fairfax BP, Knight JC, Gupta R, Thompson PJ, Holt P, Sly P, Hirschhorn JN, Blekic M, Weidinger S, Hakonarsson H, Stefansson K, Heinrich J, Postma DS, Custovic A, Pennell CE, Jarvelin MR, Koppelman GH, Timpson N, Ferreira MA, Bisgaard H, Henderson AJ; Australian Asthma Genetics Consortium (AAGC); EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
Nat Genet. 2013;45(8):902-6
Cifuentes L, Kiritsi D, Chen W, Pennino J, Ring J, Weidinger S, Has C
A case of junctional epidermolysis bullosa with prurigo-like lesions and reduction of collagen XVII and filaggrin.
Br J Dermatol. 2013;169(1):195-8
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
J Allergy Clin Immunol. 2013;132(5):1121-9

2012

Rebane A, Zimmermann M, Aab A, Baurecht H, Koreck A, Karelson M, Abram K, Metsalu T, Pihlap M, Meyer N, Fölster-Holst R, Nagy N, Kemeny L, Kingo K, Vilo J, Illig T, Akdis M, Franke A, Novak N, Weidinger S, Akdis CA.
Mechanisms of IFN-?-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis
J Allergy Clin Immunol. 2012;129(5):1297-306
Fölster-Holst R, Weidinger S
Neues und Bewährtes zur Therapie des atopischen Ekzems
Allergo Journal 2012;21:404-415
Liedén A, Winge MC, Sääf A, Kockum I, Ekelund E, Rodriguez E, Fölster-Holst R, Franke A, Illig T, Tengvall-Linder M, Baurecht H, Weidinger S, Wahlgren CF, Nordenskjöld M, Bradley M
Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.
PLoS One 2012;7(11):e49694
Ellinghaus E, Stuart PE, Ellinghaus D, Nair RP, Debrus S, Raelson JV, Belouchi M, Tejasvi T, Li Y, Tsoi LC, Onken AT, Esko T, Metspalu A, Rahman P, Gladman DD, Bowcock AM, Helms C, Krueger GG, Koks S, Kingo K, Gieger C, Wichmann HE, Mrowietz U, Weidinger S, Schreiber S, Abecasis GR, Elder JT, Weichenthal M, Franke A.
Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL.
J Invest Dermatol 2012;132(4):1133-40
Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Kõks S, Kingo K, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Abecasis GR, Weidinger S, Nikolaus S, Schreiber S, Elder JT, Weichenthal M, Nothnagel M, Franke A.
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.
Am J Hum Genet 2012;90(4):636-47
Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, Schalkwijk J, Ståhle M, Burden AD, Smith CH, Cork MJ, Estivill X, Bowcock AM, Krueger GG, Weger W, Worthington J, Tazi-Ahnini R, Nestle FO, Hayday A, Hoffmann P, Winkelmann J, Wijmenga C, Langford C, Edkins S, Andrews R, Blackburn H, Strange A, Band G, Pearson RD, Vukcevic D, Spencer CC, Deloukas P, Mrowietz U, Schreiber S, Weidinger S, Koks S, Kingo K, Esko T, Metspalu A, Lim HW, Voorhees JJ, Weichenthal M, Wichmann HE, Chandran V, Rosen CF, Rahman P, Gladman DD, Griffiths CE, Reis A, Kere J; Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, Nair RP, Franke A, Barker JN, Abecasis GR, Elder JT, Trembath RC.
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
Nat Genet. 2012;44(12):1341-8
Arnold M, Hartsperger ML, Baurecht H, Rodríguez E, Wachinger B, Franke A, Kabesch M, Winkelmann J, Pfeufer A, Romanos M, Illig T, Mewes HW, Stümpflen V, Weidinger S.
Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.
BMC Genomics. 2012;2(9):1067-75

2011

Sun LD, Xiao FL, Li Y, Zhou WM, Tang HY, Tang XF, Zhang H, Schaarschmidt H, Zuo XB, Foelster-Holst R, He SM, Shi M, Liu Q, Lv YM, Chen XL, Zhu KJ, Guo YF, Hu DY, Li M, Li M, Zhang YH, Zhang X, Tang JP, Guo BR, Wang H, Liu Y, Zou XY, Zhou FS, Liu XY, Chen G, Ma L, Zhang SM, Jiang AP, Zheng XD, Gao XH, Li P, Tu CX, Yin XY, Han XP, Ren YQ, Song SP, Lu ZY, Zhang XL, Cui Y, Chang J, Gao M, Luo XY, Wang PG, Dai X, Su W, Li H, Shen CP, Liu SX, Feng XB, Yang CJ, Lin GS, Wang ZX, Huang JQ, Fan X, Wang Y, Bao YX, Yang S, Liu JJ, Franke A, Weidinger S, Yao ZR, Zhang XJ
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population
Nat Genet. 2011;Epub ahead of print
Romanos M, Buske-Kirschbaum A, Fölster-Holst R, Gerlach M, Weidinger S, Schmitt J
Itches and scratches - is there a link between eczema, ADHD, sleep disruption and food hypersensitivity?
Allergy 2011;Epub ahead of print
Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C, von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S, Wichmann HE, Heinrich J, Weidinger S; GINIplus and LISAplus study groups
Predictive value of food sensitization and filaggrin mutations in children with eczema
J Allergy Clin Immunol 2011;Dec;128(6):1235-1241
Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P; Australian Asthma Genetics Consortium (AAGC), Pourcain BS, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C; The Genetics of Overweight Young Adults (GOYA) Consortium, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM; the Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Weidinger S.
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Nat. Genet. 2011;44(2):187-192
Proksch E, Weidinger S.
New insights into the pathogenesis of sensitive skin.
Hautarzt 2011;62(12):900-5
De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI, Georas SN, Cheadle C, Berger AE, Zhang K, Vidyasagar S, Yoshida T, Boguniewicz M, Hata T, Schneider LC, Hanifin JM, Gallo RL, Novak N, Weidinger S, Beaty TH, Leung DY, Barnes KC, Beck LA
Tight junction defects in patients with atopic dermatitis.
J Allergy Clin Immunol. 2011;127(3):773-86
Rodríguez E, Eyerich K, Weidinger S.
Genetics of common chronic inflammatory skin diseases : An update on atopic dermatitis and psoriasis
Hautarzt 2011;62(2):107-18
Naumann A, Söderhäll C, Fölster-Holst R, Baurecht H, Harde V, Müller-Wehling K, Rodríguez E, Ruether A, Franke A, Wagenpfeil S, Novak N, Mempel M, Kalali BN, Allgaeuer M, Koch J, Gerhard M, Melén E, Wahlgren CF, Kull I, Stahl C, Pershagen G, Lauener R, Riedler J, Doekes G, Scheynius A, Illig T, von Mutius E, Schreiber S, Kere J, Kabesch M, Weidinger S.
A comprehensive analysis of the COL29A1 gene does not support a role in eczema.
J Allergy Clin Immunol 2011;127(5):1187-94
Maintz L, Yu CF, Rodríguez E, Baurecht H, Bieber T, Illig T, Weidinger S, Novak N.
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities.
Allergy 2011;66(7):893-902
Reginald K, Westritschnig K, Linhart B, Focke-Tejkl M, Jahn-Schmid B, Eckl-Dorna J, Heratizadeh A, Stöcklinger A, Balic N, Spitzauer S, Niederberger V, Werfel T, Thalhamer J, Weidinger S, Novak N, Ollert M, Hirschl AM, Valenta R.
Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses.
J Allergy Clin Immunol 2011;128(1):82-91
Bussmann C, Weidinger S, Novak N.
Genetics of atopic dermatitis.
J Dtsch Dermatol Ges 2011;9(9):670-6
Eyerich S, Onken AT, Weidinger S, Franke A, Nasorri F, Pennino D, Grosber M, Pfab F, Schmidt-Weber CB, Mempel M, Hein R, Ring J, Cavani A, Eyerich K.
Mutual antagonism of T cells causing psoriasis and atopic eczema.
N Engl J Med 2011;365(3):231-8
Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T.
Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
PLoS Genet 2011;7(8):e1002215
Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, van Diemen CC, Dubois PC, Edkins S, Fölster-Holst R, Fransen K, Glass DN, Heap GA, Hofmann S, Huizinga TW, Hunt S, Langford C, Lee J, Mansfield J, Marrosu MG, Mathew CG, Mein CA, Müller-Quernheim J, Nutland S, Onengut-Gumuscu S, Ouwehand W, Pearce K, Prescott NJ, Posthumus MD, Potter S, Rosati G, Sambrook J, Satsangi J, Schreiber S, Shtir C, Simmonds MJ, Sudman M, Thompson SD, Toes R, Trynka G, Vyse TJ, Walker NM, Weidinger S, Zhernakova A, Zoledziewska M; Type 1 Diabetes Genetics Consortium; UK Inflammatory Bowel Disease (IBD) Genetics Consortium; Wellcome Trust Case Control Consortium, Weersma RK, Gough SC, Sawcer S, Wijmenga C, Parkes M, Cucca F, Franke A, Deloukas P, Rich SS, Todd JA, van Heel DA.
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry
Nat Genet 2011;44(1):3-5

2010

Jungersted JM, Scheer H, Mempel M, Cifuentes L, Baurecht H, Høgh JK, Hellgren LI, Jemec GBE, Agne T, Weidinger S
Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
Allergy 2010;65:911-8

2009

Esparza-Gordillo J*, Weidinger S*, Fölster-Holst R, Bauerfeind A, Ruschendorf F, Patone G, Rhode K, Marenholz I, Schulz1 F, Hübner N, Wahn U, Schreiber S, Franke A, Vogler R, Baurecht H, Novak N, Rodriguez E, Illig T, Lee YA, Rüther A
A common variant on chromosome 11q13 is associated with atopic dermatitis
Nat Genet 2009;41:596-601
Rodriguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S
Meta analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease
J Allergy Clin Immunol 2009;123:1361-70

2008

Weidinger S, Baurecht H, Wagenpfeil S,, Henderson J, Novak N, Sandilands A, Chen H, Rodriguez E, O’Regan GM, Watson R, Liao H, Zhao Y, Barker JNWN, Allen M, Reynolds N, Meggitt S, Northstone K, Smith GD, Strobl C, Stahl C, Kneib T, Klopp N, Bieber T, Behrendt H, Palmer CNA, Wichmann HE, Ring J, Illig T, McLean WHI, Irvine AD
Analysis of the individual and aggregate genetic contributions of previously identified SPINK5, KLK7 and FLG polymorphisms to eczema risk
J Allergy Clin Immunol 2008;122:560-8
Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, Gohlke H, Wagenpfeil S,, Ollert M, Ring J, Behrendt H, Heinrich J, Novak N, Bieber T, Kramer U, Berdel D, von Berg A, Bauer CP, Herbarth O, Koletzko S, Prokisch H, Mehta , Meitinger T, Depner M, von Mutius E, Liang L, Moffatt M, Cookson WO, Kabesch M, Wichmann HE, Illig T
Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus
PLoS Genet 2008;4(8):e1000166
Weidinger S, O’Sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland S, McLean WHI, von Mutius E, Irvine AD, Kabesch M.
Filaggrin mutations, atopic eczema, hay fever and asthma in children
J Allergy Clin Immunol 2008;121:1203-1209
Novak N, Baurecht H, Schäfer T, Rodriguez E, Wagenpfeil S, Klopp N, Heinrich J, Behrendt H, Ring J, Wichmann E, Illig T, Weidinger S
Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel
J Invest Dermatol 2008;128:1430-5

2007

Keine Einträge

2006

Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CN, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WH, Novak N
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
J Allergy Clin Immunol 2006;118:214-9
Akdis M, Bieber T, Bindslev-Jensen C, Boguniewicz M, Eigenmann P, Hamid Q, Kapp A, Leung DYM, Lipozencic J, Luger T, Muraro A, Novak N, Platt-Mills T, Rosenwasser L, Scheynius A, Simons E, Spergel J, Turjanmaa K, Wahn U, Weidinger S, Werfel T, Zuberbier T
Diagnosis and treatment of atopic dermatitis in children and adults. European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Group
J Allergy Clin Immunol 2006;118:152-69

2005

Weidinger S, Klopp N, Rümmler L, Wagenpfeil S, Novak N, Baurecht HJ, Groer W, Darsow U, Heinrich J, Gauger A, Schafer T, Jakob T, Behrendt H, Wichmann HE, Ring J, Illig T
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
J Allergy Clin Immunol 2005;116:177-184

2004

Weidinger S, Klopp N, Wagenpfeil S, Rümmler L, Schedel M, Kabesch M, Schäfer T, Darsow U, Jakob T, Behrendt H, Wichmann HE, Ring J, Illig T
Association of a STAT 6 haplotype with elevated serum IgE levels in a population-based cohort of caucasian adults
J Med Genet 2004;41:658-663

2003

Keine Einträge

2002

Keine Einträge

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